The CaSB major consists of a methodology core (7 courses: 27 units) and a concentration (min. 5 courses: 20 units).

CaSB Major Sheet

IMPORTANT: CasB is currently in the process of revising the concentration requirements. More info on the proposed revision can be found here.

Please reference the CaSB Major Sheet for major course requirements, concentration information, and department policies, including information on how to graduate with honors.

NOTE: The CaSB Major Sheet is reflective of requirements effective Fall 2021 and forward.  For all students admitted to the major prior to Fall 2021, please consult your Degree Audit Report and the CaSB Departmental Counselor for your major requirements.

Computational & Systems Biology (CaSB) Major Methodology Core Upper Division Requirements (Effective Fall 2021)

Gateway I: C&S BIO/COM SCI/BIOENGR M184 (2 Units, Graded Pass/No Pass)
Gateway II: C&S BIO/COM SCI 185 (4 Units)
Probability: STATS 100A OR MATH 170E OR EC ENGR 131A (4 Units)
Statistics: STATS 100B OR BIOSTATS 100A (4 Units)
Biological Modeling: C&S BIO M150 (5 Units)
Capstone Series (2 courses, pick one option)**:

Option 1: C&S BIO 199 (4 Units) and C&S BIO M187 (4 Units)

Option 2: C&S BIO 198A (4 Units) and C&S BIO 198B (4 Units)

Option 3: C&S BIO 195 (4 Units) and C&S BIO M187 (4 Units)

**Students admitted to the major (not the pre-major) prior to Fall 2020 are required to complete just one course: C&S BIO M187.

Concentrations

IMPORTANT: CasB is currently in the process of revising the concentration requirements. More info on the proposed revision can be found here.

Required Concentration Courses:

  • COM SCI CM121
  • COM SCI CM124
  • MCD BIO 165A OR MCD BIO 144
  • PHYSCI 125 OR MCD BIO 187AL
  • Elective from list of approved Bioinformatics electives

Learn more about the Bioinformatics concentration

Required Concentration Courses:

  • COM SCI CM121
  • COM SCI 180
  • COM SCI M146 OR STATS 161 OR STATS 101C
  • Elective from list of approved Biological Data Sciences electives
  • Elective from list of approved Biological Data Sciences electives

Learn more about the Biological Data Sciences concentration

Required Concentration Courses:

  • BIOENGR 100
  • BIOENGR C102 or 110
  • EC ENGR 133A OR MATH 151A
  • C&S BIO M186/COM SCI CM186/BIOENGR CM186/EE BIOL M178
  • Elective from list of approved Biomedical Systems electives

Learn more about the Biomedical Systems concentration

Required Concentration Courses:

  • NEUROSC M101A
  • NEUROSC M101B
  • NEUROSC 102 OR EC ENGR 113 OR MATH 155
  • C&S BIO M186/COM SCI CM186/BIOENGR CM186/EE BIOL M178 OR COM SCI/BIOENGR M182
  • Elective from list of approved Neurosystems electives

Learn more about the Neurosystems concentration

Required Concentration Courses:

  • EE BIOL 170 OR PHYSCI 166
  • MCD BIO  100 OR MCD BIO 144 OR MCD BIO 165A
  • PHYSCI 125 OR MCD BIO 187AL
  • C&S BIO M186/COM SCI CM186/BIOENGR CM186/EE BIOL M178
  • Elective from list of approved Systems Biology electives

Learn more about the Systems Biology concentration

Students also have the option to pursue a Customized concentration.

NOTE: For those following the Computers & Biosystems concentration (phased out as of Spring 2019), please check your Degree Audit Report (DAR) for remaining requirements.

Capstone Research

As part of the Capstone requirement, students are expected to complete, at minimum, 2 quarters of research or similar internship project experience supervised by a UCLA faculty member while taking their Capstone courses. Students are advised, however, to start early, ideally in their junior year. It is recommended that students complete at least a year (or more) of research/project experience by the time they complete their second Capstone course. This helps ensure that students have sufficient material for their senior thesis. Please see the following pages for additional information:

Capstone Courses & Research Expectations

Major Methodology Core Course Planning

The Gateway and Capstone courses that are part of the Major Methodology Core are only offered in certain quarters and are designed to be taken in a certain sequence. Students are advised to take C&S BIO M184 (Fall), 185 (Winter), and M150 (Spring) in their 2nd or 3rd year. Students are advised to take their two Capstone courses during their 4th year, though a few students may take them in their 3rd year. C&S BIO M187 is typically offered in Spring quarter.

The timeline below illustrates the advised order of courses and research expectations.


When planning major coursework, students must be mindful of pre-requisites. Some courses required for the CaSB major and its concentrations have additional pre-requisites that are not part of the CaSB major or pre-major curriculum.

The flowcharts below are meant to help students plan out major coursework by depicting the requisites for each methodology core requirement. These flowcharts were last updated September 2021. Always check the Registrar’s Course Descriptions for the most up-to-date requisites.


Additionally, students must be mindful of when classes are offered (i.e., which quarters). CaSB compiles a tentative list of upper-division course offerings prior to each academic year. This list is tentative and subject to change by the departments offering each course. Students should check the Schedule of Classes or with respective departments for the most up-to-date course offerings.

Tentative Schedule of Upper-Division Course Offering AY 21-21 (last updated June 2021)

It is recommended that students meet with their Departmental Counselor regularly to plan out major coursework.

Other Important Information

All major courses must be taken for a letter grade, C or better, with the exception of C&S BIO/COM SCI/BIOENGR M184 which is only offered on a Pass/No Pass basis.^
^CaSB made a temporary exception allowing pre-major courses taken between Spring 2020 and Summer 2021 to be taken for a Pass grade. More details on this exception can be found here.

Students must have a minimum 2.0 GPA in upper-division major coursework to graduate.

Students who receive a C- or below in a major course must either repeat the course or petition to have the lower grade count for the major. More information on petitioning can be found here.

Students are subject to any requirement changes in the major until they are officially admitted to the major.